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Other innate immunity components in fish mucusThere are also a few important components of fish epidermal mucus which play an important role in innate immunity of fishes such as C-reactive proteins (CRPs), transferrin, ALP, complement proteins, etc. CRPs belong to a family of multifunctional proteins (pentraxins) and are capable of binding various ligands in a Ca2+ dependent binding affinity. Th..

Antimicrobial peptidesAntimicrobial peptides are increasingly recognized as a critical factor in host defence mechanism and found in organisms ranging from microbes, plants to animal species (Fernandes et al., 2004; Kennedy et al., 2009). It also plays an important role in fish when compared with mammals as fish rely more on their innate immune system (Hancock, 1997; Hancock and Scott, 2000). Fi..

Role of skin mucus components in innate immunityThe major function of the mucus appears to provide the effective separation between internal and external environment of fish, abrasion resistance and primary defense against the numerous aquatic pathogens by virtue of its components which include proteases, AMPs, lysozyme, CRP. These are discussed in detail below. ProteasesProtease refers to a gro..

IntroductionThe aquaculture industries with high densities of fishes are susceptible to diseases caused by many pathogens. Fish possess numerous distinct and complex defense mechanisms to protect themselves from these pathogenic infections amongst which fish skin mucus acts as the first line of physical defense against pathogens (Wang et al., 2011). The fish skin mucus provides a stable physical..