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Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses(진행중)

INTRODUCTIONThe innate immune system constitutes the first line of host defense during infection and therefore plays a crucial role in the early recognition and subsequent triggering of a proinflammatory response to invading pathogens (242). The adaptive immune system, on the other hand, is responsible for elimination of pathogens in the late phase of infection and in the generation of immunolog..

카테고리 없음 2025.04.06

Fish pathogen bacteria: Adhesion, parameters influencing virulence and interaction with host cells(진행중)

1. IntroductionThere is an increasing worldwide demand for seafood due to the awareness of fish as an important protein source for a growing population. Wild fisheries are currently in a state of decline because of overfishing, climate change, pollution and marine habitat destruction, among other factors. However, aquaculture is rising all around the world. Du to commercial and production reason..

카테고리 없음 2025.04.01

[Chapter 3] Pathogenesis of Viral Infections and Diseases - MECHANISMS OF VIRAL INJURY ANDDISEASE

MECHANISMS OF VIRAL INJURY AND DISEASEThe most common adaptation of a virus to a host involves infection, spread, and shedding with minimal if any adverse effects on the host. Medically relevant virus infections are distinct in that infection causes tissue injury and thus disease (Fig. 3.8). FIGURE 3.8 Potential mechanisms by which steps in the virus replication cycle may cause injury to cells T..

[Chapter 3] Pathogenesis of Viral Infections and Diseases - MECHANISMS OF VIRAL INFECTION AND VIRUS DISSEMINATION

Viral infection is not synonymous with disease, as many viral infections are subclinical (syn., asymptomatic, inapparent), whereas others result in disease of varying severity that is typically accompanied by characteristic clinical signs in the affected host (Fig. 3.1).  Amongst many other potentially contributing factors, the outcome of the virus host encounter is essentially the product of th..

[Chapter 2] Virus Replication - Entry and Uncoating

In the previous chapter, viruses were defined as obligate intracellular parasites that are unable to direct any independent biosynthetic processes outside the host cell. It was further noted that the genetic complexity of viruses varies greatly between individual virus families, ranging from those viruses that encode only a few proteins to others that encode several hundred proteins. Given this ..