DEEP WORK

INTRODUCTION The mucosal surfaces of teleosts (bony fishes) are the major interface between fishes and their immediate environment and serve as primary sites of entry for most pathogens. The mucosal surfaces of fishes include the epithelia and associated tissues of the gills, skin, gut, and the reproductive tract.  In mammals, the mucosal system consists of an integrated network of tissues with ..

IntroductionThe vertebrate immune system is a large, complex network that includes multiple tissues, organs, cells and molecules focusing on host defense (Zimmerman, Vogel, & Bowden, 2010). The cells and molecules of the immune system are equipped to recognize and destroy foreign substances, in particular, pathogens, thus protecting organisms against diseases and maintaining homeostasis (Chaplin..

5. SIGNALING PATHWAYS IN THE DIFFERENTIATION OF CD4 AND CD8 T CELLSAs individual CD4 T cells commit to the Th1 or Th2 effector lineage to the exclusion of the other lineage, they have provided a well-utilized model in which to study cellular and molecular events involved in cell fate choices. Much less is known regarding the Th17 fate choice, although knowledge in this area is rapidly accruing. ..