DEEP WORK

TERMS COMMONLY USED TO DESCRIBE FORMALIN-FIXED, PARAFFIN-EMBEDDED TISSUES There are terms that you will need to become familiar with when interpreting either your own or other people’s data using either in situ hybridization or immunohistochemistry. These terms are discussed next. ATROPHYAtrophy refers to the thinning of a specific type of tissue. It usually refers to epithelia. Since the epithe..

PART ONE: THE DIFFERENT CELL TYPES IN FORMALIN-FIXED, PARAFFIN-EMBEDDED TISSUES EPITHELIAL CELLSEpithelial cells are the most abundant in the body and have many important functions. For example, they cover our skin and line the gastrointestinal tract from top to bottom. They are also the progenitor cell for what is by far the most common type of cancer in humans: the carcinomas. The different ty..

3. Cell surface structure mediating bacterial cell adhesion As described above, cell surface structures directly affect microbial adhesion to solid surfaces. EPS and proteinous cell appendages have functions for bridging between the cell body and a substratum. While EPS is important for development of biofilm structure rather than for cell adhesion, proteinous cell appendages are often essential..