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Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies

1. IntroductionInfectious diseases caused by bacteria, viruses, fungi, and parasites can be categorized into extracellular or intracellular pathogens from an immunopathological perspective. Most encounters with these pathogenic agents lead to an acute infection, followed by the development of clinical signs. These infections are relatively brief, and in a healthy host, following onset of appropr..

Strategies of Intracellular Pathogens for Obtaining Iron from the Environment(보류)

1. IntroductionIntracellular pathogens are organisms that are capable of growing and reproducing inside host cells. These pathogens can be divided into facultative intracellular parasites and obligate intracellular parasites [1]. Intracellular microorganisms are very important because they cause many human diseases, resulting in significant morbidity and mortality. Some examples of infectious di..

A Comprehensive Review of Signal Peptides: Structure, Roles, and Applications(진행중)

Abbreviations: SP: Signal peptide, SPase: Signal peptidase, ER: endoplasmic reticulum, LHCGR: Human luteinizing hormone receptor, CADA: Cyclotriazadisulfonamide, hCD4: Human CD4, aa: amino acid, PMF: proton motive force, VSV-G: vesicular stomatitis virus G-protein, MBP: maltose-binding protein, ALP: Alkaline phosphatase, Cel-CD: cellulase catalytic domain, RBP: ribose-binding peptide, GM-CSF: gr..

Teleost fish interferons and their role in immunity(보류)

1. IntroductionInterferons (IFNs) are virus inducible cytokines that share antiviral properties. IFNs are classified into three subfamilies, type I, II and III, on the basis of the cognate receptors they interact with and the subsequent immune responses they initiate. They differ also in genomic structure and the cell sources producing them. In tetrapods, both type I and III families contain mul..